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Blog Summary
Introduction
Adherence to medical treatments among HIV/AIDS-positive patients is a critical determinant of treatment outcomes and the overall progression of the disease. In Nasarawa State, Nigeria, like many other regions globally, ensuring consistent adherence to antiretroviral therapy (ART) presents a formidable challenge.
Despite the availability of increasingly effective treatment options, the persistence of poor adherence behaviors threatens the efficacy of these interventions and undermines efforts to curb the HIV/AIDS epidemic. Factors contributing to suboptimal adherence in this context are multifaceted, encompassing socioeconomic, cultural, and healthcare system-related barriers.
Economic constraints may hinder individuals’ ability to access treatment regularly or afford ancillary services, while cultural beliefs and stigma surrounding HIV/AIDS may foster secrecy and reluctance to seek care openly. Additionally, logistical challenges such as long distances to healthcare facilities, stockouts of medications, and inadequate patient education programs may further impede adherence efforts.
Understanding the Importance of Adherence
Adherence to ART is vital for suppressing viral replication, improving survival rates, and enhancing the quality of life for people living with HIV (PLWH). Failure to adhere to prescribed treatment regimens can lead to inadequate viral suppression, immunologic failure, disease progression, and the development of drug resistance. Given the rapid replication rate of the HIV virus, strict adherence to medication is imperative to achieve favorable outcomes.
Factors Affecting Adherence
Behavioral Barriers
- Several behavioral factors contribute to poor adherence among HIV/AIDS-positive patients. These may include depression, low health literacy, stigma, discrimination, and inconsistent access to medication.
- Behavioral barriers can significantly impact a patient’s willingness and ability to adhere to their treatment regimen.
Structural Barriers
Structural barriers such as poverty, lack of transportation, and limited access to healthcare facilities can hinder adherence to ART. Patients facing socioeconomic challenges may struggle to afford medication or attend regular clinic visits, leading to interruptions in treatment.
Psychosocial Barriers
Psychosocial factors like stress, denial, and non-disclosure of HIV status can also influence adherence behavior. Patients experiencing psychosocial barriers may struggle with acceptance of their diagnosis or fear of stigma, which can affect their engagement with healthcare services.
Specific Objectives of the Study
- Assess the level of knowledge of HIV/AIDS positive patients on the medical management of HIV/AIDS.
- Identify misconceptions regarding HIV/AIDS among HIV positive patients.
- Ascertain contributing factors for poor adherence in the medical treatment of HIV/AIDS.
- Determine the duration HIV/AIDS positive patients stay in treatment before defaulting.
Methodology
Research Design
A cross-sectional descriptive design was employed to assess factors contributing to poor adherence among HIV/AIDS positive patients attending ART clinics in Nasarawa State.
Research Setting
The study was conducted in ART clinics across Nasarawa State, which is located in the North Central geopolitical zone of Nigeria.
Target Population
The target population comprised all HIV/AIDS positive clients attending ART clinics in Nasarawa State.
Sample and Sampling Technique
A sample of 400 HIV/AIDS positive patients was selected using a simple random sampling technique. Participants were drawn from selected ART clinics in Nasarawa State.
Inclusion and Exclusion Criteria
Participants included in the study were HIV positive clients properly enrolled in care at ART facilities in Nasarawa State. Individuals not living with HIV/AIDS or not properly enrolled in care were excluded from the study.
Instrument for Data Collection
A self-designed, structured questionnaire was used to collect data. The questionnaire included sections on socio-demographic data, knowledge of HIV/AIDS management, misconceptions, and factors affecting adherence.
Validity and Reliability
The questionnaire underwent face validity and reliability testing to ensure its accuracy and consistency in measuring the intended variables.
Procedure for Data Collection
The researcher visited ART clinics to distribute and collect questionnaires from respondents. Data collection was carried out over two visits to ensure adequate participation and response rates.
Method of Data Analysis
Data collected were analyzed using MINITAB 14 and presented using frequency distribution tables to identify patterns and trends.
Ethical Consideration
Permission was obtained from relevant authorities, and informed consent was obtained from participants before data collection. Confidentiality and privacy of participants were maintained throughout the study.
Findings and Discussion
Level of Knowledge of HIV/AIDS Positive Patients
Findings indicate a high level of knowledge among respondents regarding the medical management of HIV/AIDS. The majority obtained information from health workers and recognized the importance of adherence to treatment.
Misconceptions Regarding HIV/AIDS
A significant proportion of respondents held misconceptions about HIV/AIDS, including doubts about the reliability of HIV antibody tests and beliefs in alternative treatment methods such as herbal medicine.
Contributing Factors for Poor Adherence
Stigma and discrimination emerged as major contributors to poor adherence, followed by forgetfulness. Structural and psychosocial barriers also played significant roles in hindering adherence to treatment.
Duration of Treatment Before Defaulting
Most defaulters discontinued treatment within the first three months of initiation, with stigma and unforeseen drug reactions cited as potential reasons for non-adherence.
Implications for Nursing
Addressing poor adherence requires a multifaceted approach that includes health education, counseling, and support services. Nurses play a crucial role in promoting adherence by providing accurate information, addressing misconceptions, and offering psychosocial support to patients.
Conclusion
Efforts to enhance adherence to antiretroviral therapy (ART) among HIV/AIDS positive patients attending clinics in Nasarawa State, Nigeria, have encountered persistent challenges. Despite the availability of treatment, structural impediments such as limited access to healthcare facilities, especially in rural areas, coupled with economic constraints and transportation issues, hinder consistent adherence.
Additionally, behavioral factors such as forgetfulness, stigma, and misconceptions about ART contribute to suboptimal adherence rates. Furthermore, psychosocial barriers including depression, anxiety, and lack of social support networks exacerbate the challenge. Addressing these multifaceted barriers is crucial to improving treatment outcomes and promoting the overall well-being of people living with HIV/AIDS (PLWH) in Nasarawa State.
Interventions that incorporate holistic approaches, including community-based education, peer support programs, and economic empowerment initiatives, are essential to overcoming these challenges and fostering a supportive environment conducive to sustained adherence to ART regimens. By addressing structural, behavioral, and psychosocial factors, healthcare interventions can effectively enhance adherence rates and contribute to better health outcomes among PLWH in Nasarawa State.
Source: Start Your Treatment Adherence Now
References
[1]. Adegoke OA and Zerish ZN. (2013). The Complex Nature of Adherence in the Management of HIV/AIDS as a Chronic Medical Condition. Journal of Diseases. 1(1): 18-35.[2]. Aliyu N. (2014). Factors Associated with Adherence to Antiretroviral Therapy Among People Living with HIV/ AIDS Attending Federal Medical Centre, Gusau, Zamfara State. A Thesis Submitted to Post Graduate School, Ahmadu Bello University Zaria, in Partial Fulfilment of the Requirements for Award of Master of
Public Health (Field Epidemiology) Degree.
[3]. Asmare M, Aychiluhem M, Ayana M, and Jara D. (2014). Level of ART Adherence and Associated Factors among HIV Sero- Positive Adult on Highly Active Antiretroviral Therapy in Debre Markos Referral Hospital, Northwest Ethiopia. J Antivirals and Antiretrovirals. 6:120-126.
[4]. Bello SI. (2011). HIV/AIDS Patients’ Adherence to Antiretroviral Therapy in Sobi Specialist Hospital, Ilorin, Nigeria. Global Journal of Medical research. 11(2).
[5]. Bernard NM, Margaret NK, Peter KK, Ephantus WK, et al. (2011). Factors Associated with Default from Treatment Among Tuberculosis Patients in Nairobi Province, Kenya: A case control study. BMC Public Health. 11: 696.
[6]. Catherine MN, Janetta R and Seter S. (2015). Knowledge About HIV and AIDS Among Young Women. Open Journal of Nursing. 5: 558-565.
[7]. Daniel O.J, Oladapo OT, Ogundahunsi OA, Fagbenro S, et al. (2008). Default from Anti-Retroviral Treatment Programme in Sagamu, Nigeria. African Journal of Biomedical Research. 11: 221- 224.
[8]. Francois NS, Brian HH, Christiaan BB and Martie SL. (2015). The Impact of HIV/AIDS on Compliance with Antidepressant Treatment in major Depressive Disorder: A Prospective Study in a South African Private Healthcare Cohort. AIDS Research and Therapy. 12: 9.
[9]. Gugulethu M. (2008). Psychological Factors that affect Adherence to Anti-Retroviral Therapy Amongst HIV/AIDS Patients at Kalafong Hospital. Mini-Dissertation Submitted in Partial Fulfilment of the Requirements for the Degree of MA (Clinical Psychology), University of Pretoria.
[10]. Haftay G, Henock G, Mussie A and Girmatsion F. (2014). Knowledge and Misconception on HIV/AIDS and Associated Factors among Primary School Students within the Window of Opportunity in Mekelle City, North Ethiopia. International Journal of Pharma Sciences and Research. 5(11): 831-841.